Properties
Description
BMS-986165, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets IL-12, IL-13, JAK1 JH2, and Tyk2 JH2.
Molecular Formula
C20H19D3N8O3
Targets
IL-12; IL-13; JAK1 JH2: 1 nM; Tyk2 JH2: 0.2 nM
Solubility
DMSO: 27 mg/mL (63.46 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BMS-986165 is employed in research to study TYK2 inhibition and its potential in treating autoimmune diseases.