JAK inhibitor Cercosporamide, Purity ≥98%

Synonym: Cercosporamide; 131436-22-1; (-)-Cercosporamide; (9aS)-8-Acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide; JAK inhibitor

CAS Number: 131436-22-1
Compound CID: 131379

Product Size

0.5 mg; 1 mg; 2.5 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cercosporamide is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets Mnk, Pkc1, and Pkc1.

Molecular Weight

331.28

Molecular Formula

C₁₆H₁₃NO₇

Targets

Mnk; Pkc1: 50 nM; Pkc1: 7 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Cercosporamide is used in research to study eukaryotic translation initiation factor 2 alpha kinase (EIF2AK) inhibition in various disease models.