JAK inhibitor FM-381, Purity ≥98%

Synonym: FM-381; 2226521-65-7; FM381; (E)-2-Cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide; JAK inhibitor

CAS Number: 2226521-65-7
Compound CID: 122197584

Product Size

2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

FM-381, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity.

Molecular Weight

428.496

Molecular Formula

C₂₄H₂₄N₆O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (46.67 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.66 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

FM-381 can be used to study selective JAK3 inhibition and its potential in treating autoimmune diseases.