JAK inhibitor GLPG0634, Purity ≥98%

Synonym: 1206101-20-3; Filgotinib; GLPG0634; 1206161-97-8; N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide; JAK inhibitor

MDL: MFCD20527867
CAS Number: 1206101-20-3
Compound CID: 49831257

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GLPG0634, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK.

Molecular Weight

410.15

Molecular Formula

C₂₃H₁₈N₆O₂

Targets

JAK

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.09 mg/mL (0.22 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GLPG0634 can be used to study the inhibition of Janus kinase (JAK) signaling pathways.

Storage

Store at -20ºC.