JAK inhibitor JAK3-IN-1, Purity ≥98%

Synonym: JAK3-IN-1; 1805787-93-2; N-(3-{[(5-Chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-Yl)phenyl]amino}pyrimidin-4-Yl)amino]methyl}phenyl)prop-2-enamide; N-[3-[[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]methyl]phenyl]-2-propenamide; JAK inhibitor

CAS Number: 1805787-93-2
Compound CID: 92042864

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JAK3-IN-1 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets BTK, ITK, JAK1, JAK2, JAK3, and TTK.

Molecular Weight

508.02

Molecular Formula

C₂₆H₃₀ClN₇O₂

Targets

BTK: 794 nM; ITK: 1070 nM; JAK1: 896 nM; JAK2: 1050 nM; JAK3: 4.8 nM; TTK: 49 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

JAK3-IN-1 can be applied to examine selective inhibition mechanisms of JAK3.