JAK inhibitor JAK3-IN-2, Purity ≥98%

Synonym: JAK3-IN-6; 1443235-95-7; JAK3-IN-2; Ethyl 4-(3-methacrylamidophenyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate; BDBM153160; Ethyl 4-[3-(2-methylprop-2-enoylamino)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate; Selective JAK3 inhibitor 1; JAK inhibitor

CAS Number: 1443235-95-7
Compound CID: 89629876

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JAK3-IN-2, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK3.

Molecular Weight

350.378

Molecular Formula

C₁₉H₁₈N₄O₃

Targets

JAK3: 0.15 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 69 mg/mL (196.93 mM); Water: Insoluble; Ethanol: 9 mg/mL (25.68 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

JAK3-IN-2 is used to research selective JAK3 signaling inhibition.

Storage

Store at -20ºC.