JAK inhibitor JANEX-1, Purity ≥98%

Synonym: JANEX-1; 202475-60-3; WHI-P131; jak3 inhibitor i; Janex 1; 4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol; 4-(6,7-dimethoxyquinazolin-4-ylamino)phenol; JAK inhibitor

MDL: MFCD01862614
CAS Number: 202475-60-3
Compound CID: 3794

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JANEX-1, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK3.

Molecular Weight

297.31

Molecular Formula

C₁₆H₁₅N₃O₃

Targets

JAK3: 78 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 5 mg/mL (16.81 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

JANEX-1 can be used to investigate inhibition of JAK3 and its related signaling pathways.

Storage

Store at -20ºC.