JAK inhibitor Momelotinib, Purity ≥98%

Synonym: Cyt387; MOMELOTINIB; 1056634-68-4; Cyt-387; CYT 387; N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide; JAK inhibitor

MDL: MFCD16038899
CAS Number: 1056634-68-4
Compound CID: 25062766

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Momelotinib, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, and JAK3.

Molecular Weight

414.5

Molecular Formula

C₂₃H₂₂N₆O₂

Targets

JAK1: 11 nM; JAK2: 18 nM; JAK3: 155 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 67 mg/mL (161.65 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Momelotinib is utilized to study its inhibitory effects on JAK1/2 and its therapeutic potential in myeloproliferative disorders.

Storage

Store at -20ºC.