JAK inhibitor NS-018 hydrochloride, Purity ≥98%

Synonym: Ilginatinib hydrochloride; NS-018 hydrochloride; 1239358-85-0; NS-018 (hydrochloride); 6-N-[(1S)-1-(4-Fluorophenyl)ethyl]-4-(1-methylpyrazol-4-yl)-2-N-pyrazin-2-ylpyridine-2,6-diamine; hydrochloride; Ilginatinib HCl; JAK inhibitor

CAS Number: 1239358-85-0
Compound CID: 89571724

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NS-018 hydrochloride is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

425.89

Molecular Formula

C₂₁H₂₁ClFN₇

Targets

JAK1: 33 nM; JAK2: 0.72 nM; JAK3: 39 nM; Tyk2: 22 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NS-018 hydrochloride is employed in studying JAK2 and Src kinase inhibition.

Storage

Store at -20ºC.