JAK inhibitor NS-018, Purity ≥98%

Synonym: NS-018; ilginatinib; 1239358-86-1; 56R994WX4L; UNII-56R994WX4L; CHEMBL4303389; (S)-N-(1-(4-Fluorophenyl)ethyl)-4-(1-methyl-1H-pyrazol-4-yl)-N'-(pyrazin-2-yl)pyridine-2,6-diamine; JAK inhibitor

CAS Number: 1239358-86-1
Compound CID: 46866319

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NS-018 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

389.43

Molecular Formula

C₂₁H₂₀FN₇

Targets

JAK1: 33 nM; JAK2: 0.72 nM; JAK3: 39 nM; Tyk2: 22 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NS-018 can be used to explore the selective inhibition of JAK2 and Src family kinases.

Storage

Store at -20ºC.