JAK inhibitor NSC 42834, Purity ≥98%

Synonym: 195371-52-9; JAK2 Inhibitor V, Z3; NSC 42834; 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one; JAK2 Inhibitor V; JAK2 Inhibitor V Z3; NSC-42834; JAK inhibitor

MDL: MFCD00023550
CAS Number: 195371-52-9
Compound CID: 238484

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

NSC 42834 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK2-V617F, and JAK2-WT.

Molecular Weight

344.45

Molecular Formula

C₂₃H₂₄N₂O

Targets

JAK2-V617F: 28 μM; JAK2-WT: 15 μM

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

NSC 42834 can be employed to study the inhibition of JAK2 signaling pathways.