JAK inhibitor NSC 42834, Purity ≥98%

Synonym: 195371-52-9; JAK2 Inhibitor V, Z3; NSC 42834; 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one; JAK2 Inhibitor V; JAK2 Inhibitor V Z3; NSC-42834; JAK inhibitor

MDL: MFCD00023550
CAS Number: 195371-52-9
Compound CID: 238484

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NSC 42834 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK2-V617F, and JAK2-WT.

Molecular Weight

344.45

Molecular Formula

C₂₃H₂₄N₂O

Targets

JAK2-V617F: 28 μM; JAK2-WT: 15 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NSC 42834 can be employed to study the inhibition of JAK2 signaling pathways.

Storage

Store at -20ºC.