JAK inhibitor NVP-BSK805, Purity ≥98%

Synonym: NVP-BSK805; 1092499-93-8; 4-(2,6-Difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine; BSK 805; 8-(3,5-Difluoro-4-(morpholinomethyl)phenyl)-2-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxaline; 8-[3,5-Difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline; JAK inhibitor

CAS Number: 1092499-93-8
Compound CID: 46398810

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NVP-BSK805 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets FL JAK2 wt, JAK1 JH1, JAK2 JH1, JAK2 (V617F), and TYK2 JH1.

Molecular Weight

563.47

Molecular Formula

C₂₇H₂₈F₂N₆O.2HCl

Targets

FL JAK2 wt: 0.58 nM; JAK1 JH1: 31.68 nM; JAK2 JH1: 0.48 nM; JAK2 (V617F): 0.56 nM; TYK2 JH1: 18.68 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NVP-BSK805 is used to investigate selective inhibition of JAK2 activity.

Storage

Store at -20ºC.