JAK inhibitor Oclacitinib maleate, Purity ≥98%

Synonym: OCLACITINIB MALEATE; 1208319-27-0; 1640292-55-2; Oclacitinib (maleate); Apoquel; Oclacitinib maleate [USAN]; Oclacitinib Maleate(PF-03394197); JAK inhibitor

CAS Number: 1640292-55-2
Compound CID: 44631937

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Oclacitinib maleate, soluble in DMSO, water and ethanol, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

453.51

Molecular Formula

C₁₉H₂₇N₅O₆S

Targets

JAK1: 10 nM; JAK2: 18 nM; JAK3: 99 nM; Tyk2: 84 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (178.61 mM); Water: 16 mg/mL (35.28 mM); Ethanol: 81 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Oclacitinib maleate can be researched for the inhibition of JAK1 pathways in various models.

Storage

Store at -20ºC.