JAK inhibitor SAR-20347, Purity ≥98%

Synonym: SAR-20347; 1450881-55-6; 2-(2-Chloro-6-fluorophenyl)-5-((4-(morpholine-4-carbonyl)phenyl)amino)oxazole-4-carboxamide; SAR20347; 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide; 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide; JAK inhibitor

CAS Number: 1450881-55-6
Compound CID: 71727668

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SAR-20347, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

444.84

Molecular Formula

C₂₁H₁₈ClFN₄O₄

Targets

JAK1: 23 nM; JAK2: 46 nM; JAK3: 41 nM; Tyk2: 0.6 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (173.09 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SAR-20347 can be researched for its dual inhibition of JAK1 and Tyk2, with application in autoimmune disease models.

Storage

Store at -20ºC.