Properties
Description
ZM39923 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets CDK4, EGFR, JAK1, JAK3, Lck, and TGM2.
Molecular Formula
C23H25NO
Targets
CDK4: 5.0 (pIC50); EGFR: 5.6 (pIC50); JAK1: 4.4 (pIC50); JAK3: 7.1 (pIC50); Lck: 5.0 (pIC50); TGM2: 10 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ZM39923 can be employed to study the inhibition of JAK3 with potential applications in immunomodulation.