Properties
Description
JNJ-18038683 inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets human 5-HT7 receptor, and rat 5-HT7 receptor.
Molecular Formula
C26H28ClN3O7
Targets
Human 5-HT7 receptor: 8.20 (pKi, in HEK293 cells); Rat 5-HT7 receptor: 8.19 (pKi, in HEK293 cells)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
JNJ-18038683 can be used for its ability to enhance serotonin transmission and antidepressant-like behavior.
Storage
Store at -20°C, and keep desiccated.