Properties
Description
JNJ-39758979 inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets guinea pig H4 receptor, human H4 receptor, monkey H4 receptor, mouse H4 receptor, and rat H4 receptor.
Molecular Formula
C11H19N5
Targets
Guinea pig H4 receptor: 306 nM; Human H4 receptor: 12.5 nM; Monkey H4 receptor: 25 nM; Mouse H4 receptor: 5.3 nM; Rat H4 receptor: 188 nM
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
JNJ-39758979 can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
Storage
Store at -20°C, and keep desiccated.
