JNJ 42153605

Synonym: 1254977-87-1; 3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine

CAS Number: 1254977-87-1
Compound CID: 49765871

Product Size

5 mg; 10 mg; 20 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JNJ 42153605, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR2.

Molecular Weight

400.187

Molecular Formula

C₂₂H₂₃F₃N₄

Targets

mGluR2: 17 nM (EC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 4 mg/mL (9.98 mM); Water: insoluble; Ethanol: 10 mg/mL (24.97 mM)

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

JNJ 42153605 can be studied for its effect on improving sleep patterns and promoting relaxation.

Storage

Store at -20°C, and keep desiccated.