JNJ 42153605

Synonym: 1254977-87-1; 3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine

CAS Number: 1254977-87-1
Compound CID: 49765871

Product Size

5 mg; 10 mg; 20 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JNJ 42153605, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR2.

Molecular Weight

400.187

Molecular Formula

C₂₂H₂₃F₃N₄

Targets

mGluR2: 17 nM (EC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 4 mg/mL (9.98 mM); Water: insoluble; Ethanol: 10 mg/mL (24.97 mM)

Applications

JNJ 42153605 can be studied for its effect on improving sleep patterns and promoting relaxation.