JNK-c-Jun inhibitor AS601245, Purity ≥98%

Synonym: AS601245; 345987-15-7; AS-601245; 1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile; 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile; 2-(1,3-Benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile; JNK-c-Jun inhibitor

MDL: MFCD07772196
CAS Number: 345987-15-7
Compound CID: 10109823

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AS601245 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets hJNK1, hJNK2, and hJNK3.

Molecular Weight

372.45

Molecular Formula

C₂₀H₁₆N₆S

Targets

hJNK1: 150 nM; hJNK2: 220 nM; hJNK3: 70 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

AS601245 can be used for research into the inhibition of JNK and its effects on inflammatory and apoptotic pathways.