JNK-c-Jun inhibitor AS601245, Purity ≥98%

Synonym: AS601245; 345987-15-7; AS-601245; 1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile; 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile; 2-(1,3-Benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile; JNK-c-Jun inhibitor

MDL: MFCD07772196
CAS Number: 345987-15-7
Compound CID: 10109823

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AS601245 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets hJNK1, hJNK2, and hJNK3.

Molecular Weight

372.45

Molecular Formula

C₂₀H₁₆N₆S

Targets

hJNK1: 150 nM; hJNK2: 220 nM; hJNK3: 70 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AS601245 can be used for research into the inhibition of JNK and its effects on inflammatory and apoptotic pathways.

Storage

Store at -20ºC.