JNK-c-Jun inhibitor IQ 3, Purity ≥98%

Synonym: 312538-03-7; IQ-3; [(E)-Indeno[1,2-b]quinoxalin-11-ylideneamino] furan-2-carboxylate; 11H-Indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime; JNK-c-Jun inhibitor

CAS Number: 312538-03-7
Compound CID: 5405540

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IQ 3, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets CK1δ, JNK1, JNK2, and JNK3.

Molecular Weight

341.32

Molecular Formula

C₂₀H₁₁N₃O₃

Targets

CK1δ: 0.56 μM (Kd); JNK1: 0.24 μM (Kd); JNK2: 0.29 μM (Kd); JNK3: 0.066 μM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (26.36 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

IQ 3 can be utilized to study molecular pathways involving protein kinases inhibited by IQ 3.

Storage

Store at -20ºC.