JNK-c-Jun inhibitor JNK-IN-8, Purity ≥98%

Synonym: JNK-IN-8; 1410880-22-6; JNK Inhibitor XVI; JNK-IN-8 (GMP); 3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide; (E)-3-(4-(dimethylamino)but-2-enamido)-N-(3-methyl-4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide; 1644498-56-5; JNK-c-Jun inhibitor

CAS Number: 1410880-22-6
Compound CID: 57340686

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JNK-IN-8, soluble in warmed DMSO and insoluble in water and ethanol, is an inhibitor of c-jun N-terminal kinase (JNK) signaling.

Molecular Weight

507.59

Molecular Formula

C₂₉H₂₉N₇O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 91 mg/mL (179.27 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

JNK-IN-8 is applied as a tool for the selective inhibition of JNK and its role in inflammatory and apoptotic pathways.