JNK-c-Jun inhibitor TCS JNK 5a, Purity ≥98%

Synonym: 312917-14-9; TCS JNK 5a; JNK Inhibitor IX; N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide; JNK-c-Jun inhibitor

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TCS JNK 5a, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets JNK2 and JNK3.

Molecular Weight

332.42

Molecular Formula

C₂₀H₁₆N₂OS

Targets

JNK2: 6.5 (pIC₅₀); JNK3: 6.7 (pIC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 19 mg/mL (57.15 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TCS JNK 5a can be utilized to investigate the function of JNK proteins by inhibiting JNK-mediated signal transduction.