JNK-c-Jun inhibitor TCS JNK 5a, Purity ≥98%

Synonym: 312917-14-9; TCS JNK 5a; JNK Inhibitor IX; N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide; JNK-c-Jun inhibitor

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TCS JNK 5a, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets JNK2 and JNK3.

Molecular Weight

332.42

Molecular Formula

C₂₀H₁₆N₂OS

Targets

JNK2: 6.5 (pIC₅₀); JNK3: 6.7 (pIC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 19 mg/mL (57.15 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

TCS JNK 5a can be utilized to investigate the function of JNK proteins by inhibiting JNK-mediated signal transduction.

Storage

Store at -20ºC.