JP 1302 2HCl inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets human α2A-adrenoceptor, human α2B-adrenoceptor, human α2C-adrenoceptor, and rodent α2D-adrenoceptor.
Molecular Weight
441.4
Molecular Formula
C24H24N4·2HCl
Targets
Human α2A-adrenoceptor: 3150±50 nM; Human α2B-adrenoceptor: 1470±130 nM; Human α2C-adrenoceptor: 28±2 nM; Rodent α2D-adrenoceptor: 1700±200 nM
Form
Lyophilized powder
Purity
>98%
Applications
JP 1302 2HCl can be used for its antidepressant and antipsychotic-like effects.
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