Properties
Description
K-Ras (G12C) inhibitor 6, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations.
Molecular Formula
C17H22Cl2N2O3S
Solubility
DMSO: 75 mg/mL (185.03 mM); Water: Insoluble; Ethanol: 28 mg/mL (69.08 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
K-Ras(G12C) inhibitor 6 can be used to study the selective inhibition of mutant KRas G12C in cancer research.