K02288

Synonym: 1431985-92-0; K 02288; K-02288; 3-[6-Amino-5-(3, 4, 5-Trimethoxyphenyl)pyridin-3-Yl]phenol

CAS Number: 1431985-92-0
PubChem CID: 46173038

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

K02288, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK6, ALK2, ALK3, ALK4, and ALK5.

Molecular Weight

352.38

Molecular Formula

C₂₀H₂₀N₂O₄

Targets

ALK1: 1.8 nM; ALK6: 6.4 nM; ALK2: 1.1 nM; ALK3: 34.4 nM; ALK4: 302 nM; ALK5: 321 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 67 mg/mL (190.13 mM); Water: insoluble; Ethanol: insoluble

Applications

K02288 has applications in studying stem cell biology as well as in developing disease models for musculoskeletal dysplasia and cancer.