Properties
Description
Kartogenin, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets Smad4, and Smad5.
Molecular Formula
C20H15NO3
Solubility
DMSO: 54 mg/mL (170.16 mM); Water: insoluble; Ethanol: 4 mg/mL (12.6 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Kartogenin can be used as a promising candidate for promoting cartilage repair and regeneration in conditions such as osteoarthritis, where cartilage degeneration is a primary pathology.
Storage
Store at -20℃, and keep desiccated.