Kartogenin

Synonym: 4727-31-5; 2-([1, 1'-Biphenyl]-4-ylcarbamoyl)benzoic acid; 2-[(4-Phenylphenyl)carbamoyl]benzoic acid; N-Biphenyl-4-yl-phthalamic acid

CAS Number: 4727-31-5
PubChem CID: 2826191

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Kartogenin, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets Smad4, and Smad5.

Molecular Weight

317.34

Molecular Formula

C₂₀H₁₅NO₃

Targets

Smad4; Smad5

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 54 mg/mL (170.16 mM); Water: insoluble; Ethanol: 4 mg/mL (12.6 mM)

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Kartogenin can be used as a promising candidate for promoting cartilage repair and regeneration in conditions such as osteoarthritis, where cartilage degeneration is a primary pathology.

Storage

Store at -20℃, and keep desiccated.