Keap1-Nrf2 inhibitor ML-385, Purity ≥98%

Synonym: ML385; 846557-71-9; ML-385; 2-(Benzo[d][1,3]dioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)indolin-5-yl)thiazol-2-yl)acetamide; 2-Benzo[1,3]dioxol-5-yl-N-{5-methyl-4-[1-(2-methyl-benzoyl)-2,3-dihydro-1H-indol-5-yl]-thiazol-2-yl}-acetamide; Keap1-Nrf2 inhibitor

CAS Number: 846557-71-9
Compound CID: 1383822

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ML-385, soluble in DMSO and insoluble in ethanol and water, is an active small molecule compound that mediates the Keap1-Nrf2 signaling pathway.

Molecular Weight

511.6

Molecular Formula

C₂₉H₂₅N₃O₄S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (132.91 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ML-385 can be utilized for investigating the inhibition of the Nrf2-ARE signaling pathway in oxidative stress and related diseases.

Storage

Store at -20ºC.