Keap1-Nrf2 inhibitor Oltipraz, Purity ≥98%

Synonym: Oltipraz; 64224-21-1; 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione; RP 35972; Oltipraz [INN]; Oltiprazum; 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione; Keap1-Nrf2 inhibitor

MDL: MFCD00868499
CAS Number: 64224-21-1
Compound CID: 47318

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Oltipraz, soluble in warmed DMSO and insoluble in water and ethanol, is an active small molecule compound that mediates the Keap1-Nrf2 signaling pathway. It targets Nrf2.

Molecular Weight

226.34

Molecular Formula

C₈H₆N₂S₃

Targets

Nrf2

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 34 mg/mL (150.21 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Oltipraz can be used to investigate its effects as an anticarcinogen and chemoprotective agent via Nrf2 pathway activation.