Keap1-Nrf2 inhibitor Oltipraz, Purity ≥98%

Synonym: Oltipraz; 64224-21-1; 4-Methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione; RP 35972; Oltipraz [INN]; Oltiprazum; 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione; Keap1-Nrf2 inhibitor

MDL: MFCD00868499
CAS Number: 64224-21-1
Compound CID: 47318

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Oltipraz, soluble in warmed DMSO and insoluble in water and ethanol, is an active small molecule compound that mediates the Keap1-Nrf2 signaling pathway. It targets Nrf2.

Molecular Weight

226.34

Molecular Formula

C₈H₆N₂S₃

Targets

Nrf2

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 34 mg/mL (150.21 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Oltipraz can be used to investigate its effects as an anticarcinogen and chemoprotective agent via Nrf2 pathway activation.

Storage

Store at -20ºC.