Keap1-Nrf2 inhibitor RTA-408, Purity ≥98%

Synonym: Omaveloxolone; 1474034-05-3; RTA-408; RTA 408; Nrf1-activator-1; SKYCLARYS; Keap1-Nrf2 inhibitor

MDL: MFCD28167769
CAS Number: 1474034-05-3
Compound CID: 71811910

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RTA-408, soluble in DMSO and ethanol and insoluble in water, is an active small molecule compound that mediates the Keap1-Nrf2 signaling pathway. It targets Nrf2.

Molecular Weight

554.71

Molecular Formula

C₃₃H₄₄F₂N₂O₃

Targets

Nrf2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 98 mg/mL (176.66 mM); Water: Insoluble; Ethanol: 20 mg/mL (36.05 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

RTA-408 can be leveraged in research looking at its potential as an activator of Nrf2 in oxidative stress and inflammatory diseases.