Properties
Description
Ki16198, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets LPA1, and LPA3.
Molecular Formula
C24H25ClN2O5S
Targets
LPA1: 0.34 μM (Ki); LPA3: 0.93 μM (Ki)
Solubility
DMSO: 86 mg/mL (175.87 mM); Water: insoluble; Ethanol: 32 mg/mL (65.44 mM)
Applications
Ki16198 can be used as a selective antagonist of the serotonin 5-HT6 receptor.