Kinesin inhibitor, ARQ 621, Purity ≥98%

Synonym: 1095253-39-6; BCP28395; VTB25339; NSC771644; N-(3-Aminopropyl)-N-[(1R)-1-(3-anilino-7-chloro-4-oxoquinazolin-2-yl)but-3-ynyl]-3-chloro-2-fluorobenzamide

CAS Number: 1095253-39-6
Compound CID: 25110841

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ARQ 621, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin.

Molecular Weight

552.43

Molecular Formula

C₂₈H₂₄Cl₂FN₅O₂

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 89 mg/mL (161.1 mM); Water: insoluble; Ethanol: 89 mg/mL (161.1 mM)

Applications

ARQ 621 is a cytoskeletal signaling inhibitor that plays a key role in interfering with mitotic spindle formation, leading to cell cycle arrest and apoptosis in tumor cells.