Kinesin inhibitor, BAY1217389, Purity ≥98%

Synonym: 1554458-53-5; BAY 1217389; BAY-1217389; N-Cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-(3,3,3-trifluoropropylamino)imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

MDL: MFCD30502614
CAS Number: 1554458-53-5
Compound CID: 78320750

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY1217389, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Mps1.

Molecular Weight

561.5

Molecular Formula

C₂₇H₂₄F₅N₅O₃

Targets

Mps1: 0.63 nM (IC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 92 mg/mL (163.84 mM); Water: insoluble; Ethanol (warmed): 3 mg/mL (5.34 mM)

Applications

BAY1217389 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancer by disrupting mitotic spindle formation, leading to cell cycle arrest and increased cancer cell death.