Properties
Description
BAY1217389, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Mps1.
Molecular Formula
C27H24F5N5O3
Targets
Mps1: 0.63 nM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 92 mg/mL (163.84 mM); Water: insoluble; Ethanol (warmed): 3 mg/mL (5.34 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
BAY1217389 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancer by disrupting mitotic spindle formation, leading to cell cycle arrest and increased cancer cell death.
Storage
Store at -20ºC, and keep desiccated.
