Properties
Description
Dimethylenastron, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Eg5.
Molecular Formula
C16H18N2O2S
Targets
Eg5: 200 nM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 56 mg/mL (185.18 mM); Water: insoluble; Ethanol: 1 mg/mL (3.31 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Dimethylenastron is a cytoskeletal signaling inhibitor that can be used for its impact on mitosis and spindle assembly.
Storage
Store at -20ºC, and keep desiccated.
