Kinesin inhibitor, Empesertib, Purity ≥98%

Synonym: 1443763-60-7; BAY 1161909; BAY-1161909; BAY1161909; (2R)-2-(4-Fluorophenyl)-N-[4-[2-(2-methoxy-4-methylsulfonylanilino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide

CAS Number: 1443763-60-7
Compound CID: 71599640

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Empesertib, soluble in DMSO and insoluble in water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Mps1.

Molecular Weight

559.61

Molecular Formula

C₂₉H₂₆FN₅O₄S

Targets

Mps1: 1 nM (IC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 94 mg/mL (167.97 mM); Water: insoluble; Ethanol: insoluble

Applications

Empesertib is a cytoskeletal signaling inhibitor that can be used for its potential to enhance the effectiveness of DNA-damaging agents.