Properties
Description
GSK-923295, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the CENP-E.
Molecular Formula
C32H38ClN5O4
Targets
CENP-E: 3.2 nM (Ki)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 90 mg/mL (151.99 mM); Water: insoluble; Ethanol: 90 mg/mL (151.99 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
GSK-923295 is a cytoskeletal signaling inhibitor that plays a key role in cancer research to disrupt mitotic spindle formation, leading to cell cycle arrest and apoptosis in cancer cells.
Storage
Store at -20ºC, and keep desiccated.
