Properties
Description
Monastrol, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Eg5.
Molecular Formula
C14H16N2O3S
Targets
Eg5: 14 μM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 54 mg/mL (184.71 mM); Water: insoluble; Ethanol: 54 mg/mL (184.71 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Monastrol is a cytoskeletal signaling inhibitor that can be used for its ability to disrupt mitotic spindle function and induce cell death in cancer cells.
Storage
Store at -20ºC, and keep desiccated.
