Properties
Description
SB 743921, soluble in DMSO, water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the KSP, KSP(Colo205cells), KSP(MV522cells), and KSP(MX1cells).
Molecular Formula
C31H33N2O3·HCl
Targets
KSP: 0.1nM; KSP (Colo205cells): 0.07nM; KSP (MV522cells): 1.7nM; KSP (MX1cells): 0.06nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 103 mg/mL (186.08 mM); Water: 20 mg/mL (36.13 mM); Ethanol: 103 mg/mL (186.08 mM); In vivo: Saline pH 5.0, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
SB 743921 is a cytoskeletal signaling inhibitor that displays the significant potential to act as an effective anti-cancer agent due to its role in disrupting cell division and reducing tumor growth.
Storage
Store at -20ºC, and keep desiccated.
