KN-62

Synonym: 127191-97-3; (S)-4-(2-(N-Methylisoquinoline-5-sulfonamido)-3-oxo-3-(4-phenylpiperazin-1-yl)propyl)phenyl isoquinoline-5-sulfonate

CAS Number: 127191-97-3
PubChem CID: 5312126

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KN-62, soluble in DMSO and insoluble in water and ethanol, interferes with or suppresses the transmission of signals between neurons in the nervous system. It targets CaMKII.

Molecular Weight

721.8

Molecular Formula

C₃₈H₃₅N₅O₆S₂

Targets

CaMKII: 0.9 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 96 mg/mL (132.99 mM); Water: insoluble; Ethanol: insoluble

Applications

KN-62 can be used in research to elucidate the role of CaMKII in different physiological and pathological conditions.