Properties
Description
KN-93, soluble in DMSO and ethanol and insoluble in water, interferes with or suppresses the transmission of signals between neurons in the nervous system.
Molecular Formula
C26H29ClN2O4S
Solubility
DMSO: 95 mg/mL (189.6 mM); Water: insoluble; Ethanol: 20 mg/mL (39.91 mM)
Applications
KN-93 can be studied extensively for its potential effect on inhibiting the activity of CaMKII by binding to the calmodulin-binding domain of the kinase, thereby preventing its activation in response to calcium/calmodulin signaling.