Properties
Description
L-APB inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGlu4, mGlu6, mGlu7, and mGlu8.
Molecular Formula
C4H10NO5P
Targets
mGlu4: 0.13 μM (EC50); mGlu6: 1.0 μM (EC50); mGlu7: 249 μM (EC50); mGlu8: 0.29 μM (EC50)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
L-APB can be used for its ability to modulate neuronal activity and neurotransmitter release, leading to effects such as inhibition of neurotransmission.
Storage
Store at -20°C, and keep desiccated.
