Lactate dehydrogenase A (LDHA) inhibitor, (R)-GNE-140, Purity ≥98%

Synonym: 2003234-63-5; GNE140; GNE 140; (2R)-5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydropyridin-6-one; Lactate dehydrogenase A (LDHA) inhibitor

CAS Number: 2003234-63-5
Compound CID: 121225870

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

(R)-GNE-140, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting lactate dehydrogenase A (LDHA). The molecular weight of the compound is 499.04, and its molecular formula is C₂₅H₂₃ClN₂O₃S₂.

Molecular Weight

499.04

Molecular Formula

C₂₅H₂₃ClN₂O₃S₂

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 88 mg/mL (176.33 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

(R)-GNE-140 plays a key role in improving glucose metabolism and managing type 2 diabetes.