Laquinimod, Purity ≥98%

Synonym: 248281-84-7; 5-Chloro-4-hydroxy-1-methyl-2-oxo-N-ethyl-N-phenyl-1,2-dihydroquinoline-3-carboxamide; N-Ethyl-N-phenyl-5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide; 5-Chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide

MDL: MFCD08689859
CAS Number: 248281-84-7
Compound CID: 54677946

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Laquinimod, soluble in DMSO and ethanol and insoluble in water, is a potent immunomodulator. The molecular weight of the compound is 356.8, and its molecular formula is C₁₉H₁₇ClN₂O₃.

Molecular Weight

356.8

Molecular Formula

C₁₉H₁₇ClN₂O₃

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 60 mg/mL (168.16 mM); Water: insoluble; Ethanol: 1 mg/mL (2.8 mM); In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Laquinimod plays a key role in inhibiting pro-inflammatory cytokines and promoting regulatory T cells, thereby reducing neuroinflammation and preventing neuronal damage in MS.