LDN-212854

Synonym: 1432597-26-6; LDN212854; LDN 212854; 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1, 5-a]pyrimidin-3-yl)quinoline

CAS Number: 1432597-26-6
PubChem CID: 60182388

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LDN-212854, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK2, ALK3, ALK4, and ALK5.

Molecular Weight

406.5

Molecular Formula

C₂₅H₂₂N₆

Targets

ALK1: 2.4 nM; ALK2: 1.3 nM; ALK3: 85.8 nM; ALK4: 2133 nM; ALK5: 9276 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 73 mg/mL (179.59 mM); Water: insoluble; Ethanol: insoluble

Applications

LDN-212854 can be used in stem cell research due to its ability to modulate signaling pathways involved in cellular differentiation and development.