Properties
Description
LDN-212854, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK2, ALK3, ALK4, and ALK5.
Molecular Formula
C25H22N6
Targets
ALK1: 2.4 nM; ALK2: 1.3 nM; ALK3: 85.8 nM; ALK4: 2133 nM; ALK5: 9276 nM
Solubility
DMSO: 73 mg/mL (179.59 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LDN-212854 can be used in stem cell research due to its ability to modulate signaling pathways involved in cellular differentiation and development.
Storage
Store at -20℃, and keep desiccated.