Properties
Description
AS-35 is a potential leukotriene receptor antagonist. It targets LTC4, LTD4, and LTE4.
Molecular Formula
C21H20N6O4
Targets
LTC4: 8 nM (In isolated guinea pig ileum); LTD4: 4 nM (In isolated guinea pig ileum); LTE4: 3 nM (In isolated guinea pig ileum)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AS-35 can be used to investigate the role of G-protein coupled receptor 35 in inflammation and immune responses.