CD BioGlyco has specialized GlycoNano™ Platform to provide many types of Glyconanoparticle Development Services for clients. Combining the unique properties of carbohydrates and quantum dots (QDs), our company provides a specialized QD Glyconanoparticle Production Service to meet our client's research needs in the areas of biomarkers, drug delivery, and disease diagnostics.
We are committed to providing comprehensive Lex-QD nanoparticle production services to our clients worldwide, covering but not limited to:
In our lab, we use a single-step solution method to synthesize cadmium sulfide nanocrystals functionalized with Lex (Galb1-4[Fuca1-3]GlcNAc). Moreover, we provide QD nanoparticle design and synthesis services with specific glycan structure, QD size, and surface modification. For example, we provide QD nanoparticle production service for the co-functionalization of disaccharide maltose (Glca1-4Glc) and trisaccharide antigen Lex.
Our researchers optimize the optical properties, biocompatibility, and stability of the Lex-QD nanoparticles through precise regulation to ensure their stability and functionality in complex biological environments.
After purification by centrifugation and filtration, we offer professional characterization services by transmission electron microscopy (TEM), nuclear magnetic resonance (NMR), ultraviolet (UV)-visible, and fluorescence spectroscopy. Moreover, we provide particle size distribution, quantum yield, fluorescence lifetime, and glycan structure confirmation services to ensure the controllability and consistency of nanoparticle quality.
Technology: Dynamic light scattering (DLS), Fluorescence microscope with light, UV filter, Electrophoresis, TEM
Journal: Pharmaceutics
Published: 2023
IF: 4.9
Results: In this study, the researchers present the synthesis and characterization of QD nanoparticles modified using specific molecules and their application in cellular uptake. The researchers used a two-phase system and a combination of sonicated emulsions to prepare the biohybrid nanoparticles. Moreover, it was found that these synthesized biohybrid nanoparticles have the ability to be selectively targeted and delivered to specific cell types with good traceability.
Fig.1 Preparation of decorated nanoparticles. (Traverso, et al., 2023)
CD BioGlyco provides high-performance Lex-QD nanoparticles to support our clients' work in the field of biological research. We provide comprehensive after-sales service, including product performance consulting, application advice technical support, etc., to ensure that clients receive adequate help and support in the process of use. Contact us anytime for more details.
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