Properties
Description
BMS-3 targets LIM kinases, which regulate actin cytoskeleton dynamics and are involved in cell migration and cancer metastasis. It targets LIMK1 and LIMK2.
Molecular Formula
C17H12Cl2F2N4OS
Targets
LIMK1: 5 nM; LIMK2: 6 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-3 can be used to inhibit the function of LIM kinase and study its effects on cell motility and cancer invasion.