LIMK inhibitor BMS-5, Purity ≥98%

Synonym: 1338247-35-0; BMS5; LIM kinase (LIMK) inhibitor

CAS Number: 1338247-35-0
Compound CID: 56965901

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BMS-5, soluble in DMSO and ethanol and insoluble in water, targets LIM kinases, which regulate actin cytoskeleton dynamics and are involved in cell migration and cancer metastasis. It targets LIMK1 and LIMK2.

Molecular Weight

431.29

Molecular Formula

C₁₇H₁₄Cl₂F₂N₄OS

Targets

LIMK1: 7 nM; LIMK2: 8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (173.9 mM); Water: Insoluble; Ethanol: 4 mg/mL (9.27 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

BMS-5 can be used to inhibit the LIM kinase dihydrochloride signaling and study neuronal and cancer cell functions.

Storage

Store at -20ºC.