Properties
Description
R-10015, soluble in DMSO, water and ethanol, targets LIM kinases, which regulate actin cytoskeleton dynamics and are involved in cell migration and cancer metastasis. It targets human LIMK1.
Molecular Formula
C20H19ClN6O2
Targets
human LIMK1: 38 nM
Solubility
DMSO: 76 mg/mL (184.98 mM); Water: <1 mg/mL; Ethanol: 9 mg/mL (21.9 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
R-10015 functions as a RAD51 inhibitor useful for exploring homologous recombination in DNA repair.
