Cat. No.: X24-09-YM438
Lipoxygenase inhibitor, Nordihydroguaiaretic acid, Purity ≥98%
Synonym: 500-38-9; NDGA; Dihydronorguaiaretic acid; Actinex; 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol; Norhydroguaiaretic acid; Norguaiaretic acid, dihydro-; Dinorguaiaretic acid, dihydro-; 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-; NSC 4291; 4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol; Lipoxygenase inhibitor
- MDL: MFCD00002206
- CAS Number: 500-38-9
- Compound CID: 4534
Product Size
1 g; 2 g; 5 g; 10 g
Properties
Description
Nordihydroguaiaretic acid, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting lipoxygenase. The molecular weight of the compound is 302.36, and its molecular formula is C18H22O4. It targets the 5-LOX.
Molecular Formula
C18H22O4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 53 mg/mL (175.28 mM); Water: insoluble; Ethanol: 53 mg/mL (175.28 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nordihydroguaiaretic acid can be studied extensively for its potential therapeutic applications in the treatment of conditions like arthritis and atherosclerosis, by inhibiting leukotriene synthesis and reducing oxidative stress.
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