Properties
Description
Loratadine, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets B(0)AT2, and H1 receptor.
Molecular Formula
C22H23ClN2O2
Targets
B(0)AT2: 4 μM; H1 receptor
Solubility
DMSO: 15 mg/mL (39.18 mM); Water: insoluble; Ethanol: 68 mg/mL (177.6 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Loratadine can be used to relieve symptoms of allergic rhinitis, such as sneezing, runny or itchy nose, and itchy or watery eyes.
Storage
Store at -20℃, and keep desiccated.
