Properties
Description
Loratadine, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets B(0)AT2, and H1 receptor.
Molecular Formula
C22H23ClN2O2
Targets
B(0)AT2: 4 μM; H1 receptor
Solubility
DMSO: 15 mg/mL (39.18 mM); Water: insoluble; Ethanol: 68 mg/mL (177.6 mM)
Applications
Loratadine can be used to relieve symptoms of allergic rhinitis, such as sneezing, runny or itchy nose, and itchy or watery eyes.